Mixture of Experts

“The Best Project Is No Project”: What It Takes to Build a Factory

Lizzy Manzi spent seven years navigating changing requirements at SpaceX, where she eventually led construction across Los Angeles and Seattle, with a…

Nov 10 • Annelies Gamble

7

The Future of “New” Manufacturing: Building on What We Already Have

A conversation with MIT’s John Hart on AI in manufacturing and what it will take to rebuild industrial capability in the US

Nov 4 • Annelies Gamble

14

1

1

October 2026

Getting to General Robots That Don’t Suck

A Co-Written Essay With Saman Farid (Founder & CEO, Formic) and Haomiao Huang (General Partner, Matter Venture Partners)

Oct 27 • Annelies Gamble

15

2

4

The Next Bottleneck in AI for Science

A conversation with Mihai Codreanu on how AI can help turn scientific hypotheses into discoveries

Oct 20 • Annelies Gamble

21

5

Manufacturing Is a Jenga Problem

A conversation with Praveen Rao, Global Director of Manufacturing at Google Cloud, about the architecture of industrial autonomy.

Oct 13 • Annelies Gamble

12

1

Why AI Capability Isn't Always Translating to Value in Industrials

A conversation with Shiv Trisal from Databricks on how AI is changing the economics of work in industrial settings, and where there are still gaps.

Oct 6 • Annelies Gamble

8

2

September 2026

Closing the Loop Between AI Design and the Wet Lab

A conversation with Wenhao Gao about designing molecules, making them, and understanding what happened.

Sep 29 • Annelies Gamble

9

1

AI Infrastructure for Manufacturing - Notes from IMTS

Two years ago I was skeptical about how big of an impact AI could really have in manufacturing.

Sep 22 • Annelies Gamble

15

2

4

When AI Measures What Instruments Miss

The standard role of AI in science is analyzing data an instrument has already collected. But what if AI were the instrument?

Sep 15 • Annelies Gamble

7

1

Scaling Agentic Commerce

A conversation with Greg Ulrich, Mastercard's Chief AI and Data Officer

Sep 8 • Annelies Gamble

9

1

Science's Observability Problem

We’ve made designing molecules easier and cheaper than ever, but, as I wrote about here, proving those designs work in humans is increasingly becoming a…

Sep 1 • Annelies Gamble and Anna Marie Wagner

12

1

August 2026

Routing Intelligence: Prateek Jain on Long-Horizon Agents

An interview with Prateek Jain, Distinguished Scientist at Google DeepMind

Aug 25 • Annelies Gamble

11